A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation

Anastasia Knyazeva, Shuang Li, Dale P Corkery, Kasturika Shankar, Laura K Herzog, Xuepei Zhang, Birendra Singh, Georg Niggemeyer, David Grill, Jonathan D Gilthorpe, Massimiliano Gaetani, Lars-Anders Carlson, Herbert Waldmann, Yao-Wen Wu

Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2317680121. pubmed

Ultrastructural insights into the microsporidian infection apparatus reveal the kinetics and morphological transitions of polar tube and cargo during host cell invasion

Himanshu Sharma, Nathan Jespersen, Kai Ehrenbolger, Lars-Anders Carlson, Jonas Barandun

PLoS Biology. 2024 Feb 29;22(2):e3002533. pubmed

The organization of double-stranded RNA in the chikungunya virus replication organelle

Timothée Laurent, Lars-Anders Carlson.

PLOS Neglected Tropical Diseases. 2023 Jul 5;17(7):e0011404. pubmed

Type I interferon shapes brain distribution and tropism of tick-borne flavivirus

Nunya Chotiwan, Ebba Rosendal, Stefanie MA Willekens, Erin Schexnaydre, Emma Nilsson, Richard Lindqvist, Max Hahn, Ionut Sebastian Mihai, Federico Morini, Jianguo Zhang, Gregory D Ebel, Lars-Anders Carlson, Johan Henriksson, Ulf Ahlgren, Daniel Marcellino, Anna K Överby

Nature Communications. 2023 Apr 10;14(1):2007. pubmed

A 3D view of how enteroviruses hijack autophagy

Selma Dahmane, Kasturika Shankar, Lars-Anders Carlson

Autophagy. 2022 Dec 5;1-3 pubmed

Architecture of the chikungunya virus replication organelle

Timothée Laurent, Pravin Kumar, Susanne Liese, Farnaz Zare, Mattias Jonasson, Andreas Carlson, Lars-Anders Carlson

eLife 2022 Oct 19;11:e83042 pubmed

Membrane-assisted assembly and selective secretory autophagy of enteroviruses

Selma Dahmane, Adeline Kerviel, Dustin R. Morado, Kasturika Shankar, Björn Ahlman, Michael Lazarou, Nihal Altan-Bonnet, Lars-Anders Carlson

Nature Communications. 2022 Oct 10. 13, 5986. pubmed

V. cholerae MakA is a cholesterol-binding pore-forming toxin that induces non-canonical autophagy

Xiaotong Jia, Anastasia Knyazeva, Yu Zhang, Sergio Castro-Gonzalez, Shuhei Nakamura, Lars-Anders Carlson, Tamotsu Yoshimori, Dale P Corkery, Yao-Wen Wu

J Cell Biol. 2022 Dec 5;221(12):e202206040 pubmed

The Tetraspanin CD81 Is a Host Factor for Chikungunya Virus Replication

Lisa Lasswitz, Francisco J Zapatero-Belinchón, Rebecca Moeller, Kirsten Hülskötter, Timothée Laurent, Lars-Anders Carlson, Christine Goffinet, Graham Simmons, Wolfgang Baumgärtner, Gisa Gerold

mBio. 2022 Jun 28;13(3):e0073122 pubmed

Clinically observed deletions in SARS-CoV-2 Nsp1 affect its stability and ability to inhibit translation

Pravin Kumar, Erin Schexnaydre, Karim Rafie, Tatsuaki Kurata, Ilya Terenin, Vasili Hauryliuk, Lars-Anders Carlson

FEBS Letters. 2022 Apr 17 pubmed

The structure of enteric human adenovirus 41—A leading cause of diarrhea in children

Karim Rafie, Annasara Lenman, Johannes Fuchs, Anandi Rajan, Niklas Arnberg, Lars-Anders Carlson

Science Advances. 2021 Jan 8;7(2) pubmed

Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46

B David Persson, Lijo John, Karim Rafie, Michael Strebl, Lars Frängsmyr, Monika Z Ballmann, Katja Mindler, Menzo Havenga, Angelique Lemckert, Thilo Stehle, Lars-Anders Carlson, Niklas Arnberg

Proc Natl Acad Sci U S A. 2021 Jan 19;118(3) pubmed

A ribonucleotide reductase from Clostridium botulinum reveals distinct evolutionary pathways to regulation via the overall activity site

Markel Martínez-Carranza, Venkateswara Rao Jonna, Daniel Lundin, Margareta Sahlin, Lars-Anders Carlson, Newal Jemal, Martin Högbom, Britt-Marie Sjöberg, Pål Stenmark, Anders Hofer

J Biol. Chem. 2020 Nov 13;295(46):15576-15587 pubmed

ATP-dependent force generation and membrane scission by ESCRT-III and Vps4

Johannes Schöneberg, Mark Remec Pavlin, Shannon Yan, Maurizio Righini, Il-Hyung Lee, Lars-Anders Carlson, Amir Houshang Bahrami, Daniel H. Goldman, Xuefeng Ren, Gerhard Hummer, Carlos Bustamante, James H. Hurley

Science. 2018 Dec 21;362(6421):1423-1428. pubmed

Neutralizing Antibodies Inhibit Chikungunya Virus Budding at the Plasma Membrane

Jing Jin, Jesús G Galaz-Montoya, Michael B Sherman, Stella Y Sun, Cynthia S Goldsmith, Eileen T O’Toole, Larry Ackerman, Lars-Anders Carlson, Scott C Weaver, Wah Chiu, Graham Simmons

Cell Host Microbe. 2018 Aug 18. pii: S1931-3128(18)30388-3. pubmed

An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope

Jing Jin, Michael B Sherman, Daniel Chafets, Nuntana Dinglasan, Kai Lu, Tzong-Hae Lee, Lars-Anders Carlson, Marcus O Muench, Graham Simmons

PLoS Negl Trop Dis. 2018 Jul 31;12(7):e0006693 pubmed

Reconstitution of selective HIV-1 RNA packaging in vitro by membrane-bound Gag assemblies

Lars-Anders Carlson*, Yun Bai, Sarah C Keane, Jennifer A Doudna, James H Hurley*

Elife. 2016 Jun 25;5 pubmed


Negative membrane curvature catalyzes nucleation of endosomal sorting complex required for transport (ESCRT)-III assembly

Il-Hyung Lee, Hiroyuki Kai, Lars-Anders Carlson, Jay T Groves, James H Hurley

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52) pubmed

ESCRT filaments as spiral springs

Lars-Anders Carlson, Qing-Tao Shen, Mark Remec Pavlin, James H Hurley

Dev Cell. 2015 Nov 23;35(4) pubmed

Architecture and dynamics of the autophagic phosphatidylinositol 3-kinase complex

Sulochanadevi Baskaran*, Lars-Anders Carlson*, Goran Stjepanovic*, Lindsey N Young, Patricia Grob, Robin E Stanley, Eva Nogales, James H Hurley

Elife. 2014 Dec 9;3 pubmed

*equal contribution

The nucleocapsid domain of Gag is dispensable for actin incorporation into HIV-1 and for association of viral budding sites with cortical F-actin

Sarah Stauffer, Sheikh Abdul Rahman, Alex de Marco, Lars-Anders Carlson, Bärbel Glass, Heike Oberwinkler, Nikolas Herold, John AG Briggs, Barbara Müller, Kay Grünewald, Hans-Georg Kräusslich

J Virol. 2014 Jul;88(14) pubmed

In vitro reconstitution of the ordered assembly of the endosomal sorting complex required for transport at membrane-bound HIV-1 Gag clusters

Lars-Anders Carlson, James H Hurley

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42) pubmed

Endosomal sorting complex required for transport (ESCRT) complexes induce phase-separated microdomains in supported lipid bilayers

Evzen Boura, Vassili Ivanov, Lars-Anders Carlson, Kiyoshi Mizuuchi, James H Hurley

J Biol Chem. 2012 Aug 10;287(33) pubmed

Membrane budding

James H Hurley, Evzen Boura, Lars-Anders Carlson, Bartosz Różycki

Cell. 2010 Dec 10;143(6) pubmed

Cryo electron tomography of native HIV-1 budding sites

Lars-Anders Carlson, Alex de Marco, Heike Oberwinkler, Anja Habermann, John AG Briggs, Hans-Georg Kräusslich, Kay Grünewald

PLoS Pathog. 2010 Nov 24;6(11) pubmed

The three-dimensional organization of polyribosomes in intact human cells

Florian Brandt*, Lars-Anders Carlson*, F Ulrich Hartl, Wolfgang Baumeister, Kay Grünewald

Mol Cell. 2010 Aug 27;39(4) pubmed

*equal contribution

Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis

Lars-Anders Carlson, John AG Briggs, Bärbel Glass, James D Riches, Martha N Simon, Marc C Johnson, Barbara Müller, Kay Grünewald, Hans-Georg Kräusslich

Cell Host Microbe. 2008 Dec 11;4(6) pubmed

Test of relativistic time dilation with fast optical atomic clocks at different velocities

Sascha Reinhardt, Guido Saathoff, Henrik Buhr, Lars-Anders Carlson, Andreas Wolf, Dirk Schwalm, Sergei Karpuk, Christian Novotny, Gerhard Huber, Marcus Zimmermann, Ronald Holzwarth, Thomas Udem, Theodor W Hänsch, Gerald Gwinner

Nature Physics. 2007 3 (12) Google Scholar

Test of time dilation by laser spectroscopy on fast ions

Guido Saathoff, Sascha Reinhardt, Henrik Buhr, Lars-Anders Carlson, Dirk Schwalm, Andreas Wolf, Sergei Karpuk, Chistian Novotny, Gerhard Huber, Gerald Gwinner

Canadian Journal of Physics. 2005 83 (4) Google Scholar

Assessment of production conditions for efficient use of Escherichia coli in high-yield heterologous recombinant selenoprotein synthesis

Olle Rengby, Linda Johansson, Lars-Anders Carlson, Elena Serini, Alexios Vlamis-Gardikas, Per Kårsnäs, Elias SJ Arnér

Appl Environ Microbiol. 2004 Sep;70(9) pubmed